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Ozempic: Can You Stop Taking it Suddenly? | Felix Health

When you’ve been prescribed Ozempic, your healthcare practitioner will give you detailed instructions on how to use it. But can you stop taking it suddenly? 

Key takeaways:

  • If you are considering stopping Ozempic, it's important to discuss your decision with your healthcare practitioner, who can provide guidance on the appropriate steps to take.
  • Abruptly discontinuing Ozempic can lead to uncontrolled blood sugar levels, which can have adverse effects on your health.
  • Your healthcare practitioner may recommend gradually reducing the dosage of Ozempic or transitioning to an alternative treatment plan.
  • Always follow the advice and instructions of your practitioner when it comes to making changes to your medication regimen.


Taking Ozempic (semaglutide) regularly can be beneficial for those who want to bring their blood sugar levels under control. However, if you want to discontinue using Ozempic, you should consult your healthcare practitioner before stopping.

Your healthcare practitioner will assess your health status and assist you in safely and effectively discontinuing Ozempic, if appropriate. 

Depending on your overall health situation, they may suggest slowly reducing your dosage over time or an alternate course of action, such as switching medications or adjusting diet and lifestyle habits to control blood sugar levels and weight.

What happens when you stop taking Ozempic?

If you have been prescribed Ozempic but have since decided it's no longer necessary or beneficial for your condition, discussing any changes with your healthcare practitioner is key. Abruptly ceasing medication use could cause sudden shifts in blood sugar levels which could be detrimental to health if not managed properly.

Your healthcare practitioner may suggest tapering off your dosage over a while — this process usually involves decreasing the amount taken over time. They might also recommend an alternate course of action, like switching medications or adjusting diet and lifestyle habits to achieve your goals. Whichever option is taken, following these guidelines will minimize potential risks associated with suddenly stopping Ozempic.

It is also important to remember that diet and lifestyle behaviours are a factor in managing blood sugar levels and weight. Eating regular meals at consistent intervals helps keep glucose levels stable. Checking labels when shopping for food can help identify hidden sugars and fats that you might not even be aware of.

When considering any changes related to prescription medications like Ozempic, always speak with your healthcare practitioner first. It's not ideal to abruptly stop taking a medication without being advised on how to do so safely and effectively. 

Doing so may cause serious medical complications due to sudden shifts in blood sugar levels when a medication like Ozempic is stopped suddenly. As long as you keep your practitioner informed and take their advice, you can stop taking Ozempic safely.

How long can you stay on Ozempic?

The length of time that you should remain on Ozempic depends on your individual medical needs and condition. Your practitioner will assess your case to determine the most beneficial treatment plan for you, including taking Ozempic for months, or even years. Following the recommended dose and frequency is crucial to ensure optimal results with Ozempic.

Can I skip a week of Ozempic?

Skipping a week of Ozempic is not advised, and it’s important to understand why this could lead to dangerous blood sugar shifts. Too little insulin, or something else that affects how the body uses it, can cause blood sugar levels to rise. In addition to seizures or strokes, elevated glucose levels over time can increase the risk of developing heart and kidney problems, nerve damage, and eye conditions such as cataracts and diabetic retinopathy.

To avoid these health risks, it’s essential for any changes in dosage — including missed doses — to be handled with caution. The best way to do this is by consulting a healthcare practitioner first so they can advise you on the safest approach depending on your individual needs and condition.

How long does Ozempic stay in your system?

Ozempic is a long-acting medication that reaches its maximum concentration between day 1 and day 3 after your injection. If you are taking the same dose of Ozempic each week, a stable concentration of medication (ie. steady-state exposure) will occur following 4-5 weeks of once-weekly administration. This means it does not need to be taken as frequently as some other medications.

It’s important to note that Ozempic’s effects may last longer in some individuals. Your practitioner will decide the best dosage based on your medical history and body size. Following their directions carefully is essential to ensure optimal results and prevent potential risks associated with stopping the medication abruptly.

How do I stop taking Ozempic safely?

Before stopping the medication, consult your healthcare practitioner about any concerns and discuss alternative treatments or lifestyle changes to help manage your weight and/or blood glucose, with or without medications. 

Depending on individual needs, tapering off the dosage gradually over time is frequently recommended, which usually allows for a smoother transition. It is also important to continue monitoring blood sugar levels during this process, since sudden medication changes  can cause dangerous shifts in glucose levels.

If other therapies or lifestyle modifications are not suitable, a healthcare practitioner might recommend an alternate blood sugar management medication. 

They will also likely recommend monitoring glucose levels even after discontinuing Ozempic and making necessary changes such as adjusting diet or increasing exercise. Contact your healthcare practitioner immediately for advice if any adverse reactions occur while taking or discontinuing Ozempic.

It is essential to take extra precautions when stopping Ozempic due to its long-acting properties that can stay in the body for many weeks. You can safely transition off the medication without risking your health by carefully monitoring and following your healthcare practitioner's instructions.

Curious if Ozempic might be right for you? Learn more about how to get Ozempic in Canada.

WRITTEN BY
Felix Team
Updated on:
May 25, 2023
Medically reviewed by
Dr. Sarah Lasuta
Family Physician, MD, CCFP
Disclaimer

The views expressed here are those of the author and, as with the rest of the content on Health Guide, are not a substitute for professional medical advice, diagnosis, or treatment. If you have any medical questions or concerns, please talk to your healthcare practitioner.

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